- Mucosa-Associated Lymphoid Tissue (MALT) plays a crucial role in the immune defense system of mucosal surfaces, including the oral cavity.
- Its primary function is to protect mucosal surfaces from pathogens such as bacteria, viruses, and other microorganisms that enter the body through the mouth.
- MALT contains immune cells like lymphocytes and macrophages, which identify and respond to potential threats, thereby preventing infections and maintaining oral health.

- It is important to note that MALT is not involved in digestion, saliva secretion regulation, or enamel mineralization.
- These functions are carried out by other structures and systems within the oral cavity. For example, digestion begins in the mouth but is primarily facilitated by enzymes in saliva and later by the gastrointestinal tract, while saliva secretion is regulated by salivary glands and neural input. Enamel mineralization is a process related to tooth development and maintenance, managed by ameloblasts during tooth formation.

In summary, the key role of MALT in the oral cavity is its immune protective function at mucosal surfaces, helping to maintain overall oral and systemic health by serving as a first line of defense.

Reference: Robbins Basic Pathology, 10th Edition, Chapter: Immune System and Disorders, Page 85