In which of the following tissues is Type II collagen predominantly present?
Solution
Correct Answer: Option A
Type II collagen is a major structural protein predominantly found in cartilage. It plays a crucial role in providing tensile strength and maintaining the shape and integrity of cartilaginous tissues. Unlike Type I collagen, which is abundant in bone, tendon, and skin, Type II collagen is almost exclusively localized in hyaline cartilage and elastic cartilage. This type of collagen forms thin fibrils that create a dense network supporting the extracellular matrix of cartilage, allowing it to withstand compressive forces and contribute to the flexibility of the tissue.
To summarize:
- Type II collagen is the main collagen in cartilage, making up about 50-60% of the total collagen content.
- Bone, tendon, and skin primarily contain Type I collagen, which provides tensile strength and rigidity.
- The presence of Type II collagen is essential for the proper function and resilience of cartilage in joints.
Therefore, the correct answer is Option 1: Cartilage.
Reference:
Robbins Basic Pathology, 10th Edition, Chapter: Connective Tissue and Cartilage / Page 85-87