Which type of epithelium lines the mucosa of the stomach?

A Simple columnar epithelium

B Stratified squamous epithelium

C Pseudostratified ciliated columnar epithelium

D Transitional epithelium

Solution

Correct Answer: Option A

- The mucosa of the stomach is lined by simple columnar epithelium.
- This type of epithelium is specialized to perform secretory and absorptive functions essential for the digestive process.
- The simple columnar epithelial cells in the stomach are mainly mucous-secreting cells, which produce a protective mucus layer that shields the stomach lining from the corrosive effects of gastric acid and digestive enzymes.

In contrast:
- Stratified squamous epithelium is typically found in areas subject to mechanical abrasion, such as the esophagus and oral cavity, but not in the stomach.
- Pseudostratified ciliated columnar epithelium is characteristic of the respiratory tract, where cilia help in moving mucus.
- Transitional epithelium lines the urinary bladder and ureters, providing stretchable lining rather than secretory function.

Thus, the presence of simple columnar epithelium in the stomach mucosa ensures both protection and secretion vital for gastric function.

Reference: Robbins Basic Pathology, 10th Edition, Chapter 15: Stomach and Duodenum / Page 639

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