Which hormone is primarily responsible for preparing the endometrium for implantation during pregnancy?
Solution
Correct Answer: Option B
- The hormone primarily responsible for preparing the endometrium for implantation during pregnancy is Progesterone.
- After ovulation, the corpus luteum secretes progesterone, which acts on the estrogen-primed endometrium to make it suitable for the implantation of a fertilized egg.
- Estrogen initially stimulates the proliferation of the endometrial lining, but it is progesterone that transforms it into a secretory structure that can support early pregnancy.
- Luteinizing hormone (LH) is involved in triggering ovulation and sustaining the corpus luteum, but it does not directly prepare the endometrium.
- Follicle-stimulating hormone (FSH) is important in follicle development but does not have a direct role in preparing the endometrium for implantation.
In summary, the presence and action of progesterone following ovulation are crucial for the successful establishment of pregnancy by preparing the endometrium to receive and support the implanted embryo.
Reference: Robbins Basic Pathology, 10th Edition, Chapter 15 – The Female Reproductive Tract / Page 718