Which embryological layer gives rise to the lens of the eye?
Solution
Correct Answer: Option A
- The lens of the eye is derived from the surface ectoderm during embryological development.
- The process begins when the optic vesicle, an outgrowth of the neuroectoderm from the forebrain, contacts the overlying surface ectoderm.
- This interaction induces the surface ectoderm to thicken and form the lens placode.
- The lens placode then invaginates to form the lens vesicle, which ultimately develops into the mature lens.
- It is important to note that although the optic vesicle comes from neuroectoderm, it primarily forms the retina, optic nerve, and other internal ocular structures, but not the lens.
- The neural crest cells contribute to other parts of the eye, such as the corneal stroma and sclera, while mesoderm gives rise to blood vessels and extraocular muscles, but neither contributes to the lens itself.
In summary, the lens originates exclusively from the surface ectoderm, emphasizing the crucial role of epithelial-mesenchymal interactions during eye development.
Reference: Langman’s Medical Embryology, 14th Edition, Chapter 18, pages 256-258
- The process begins when the optic vesicle, an outgrowth of the neuroectoderm from the forebrain, contacts the overlying surface ectoderm.
- This interaction induces the surface ectoderm to thicken and form the lens placode.
- The lens placode then invaginates to form the lens vesicle, which ultimately develops into the mature lens.
- It is important to note that although the optic vesicle comes from neuroectoderm, it primarily forms the retina, optic nerve, and other internal ocular structures, but not the lens.
- The neural crest cells contribute to other parts of the eye, such as the corneal stroma and sclera, while mesoderm gives rise to blood vessels and extraocular muscles, but neither contributes to the lens itself.
In summary, the lens originates exclusively from the surface ectoderm, emphasizing the crucial role of epithelial-mesenchymal interactions during eye development.
Reference: Langman’s Medical Embryology, 14th Edition, Chapter 18, pages 256-258
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