- The primary role of electrolytes in human physiology is maintaining fluid balance and supporting nerve and muscle function.
- Electrolytes such as sodium, potassium, calcium, and magnesium are essential minerals that carry an electric charge when dissolved in body fluids.
- This electric charge is critical for regulating the movement of water between cells and their environment, ensuring proper hydration and cellular function.

- In addition to fluid balance, electrolytes play a key role in transmitting electrical signals along nerves and enabling muscle contractions.
- For example, potassium and sodium ions are involved in generating action potentials in nerve and muscle cells, which are necessary for communication between cells and muscle movement.
- Without a proper balance of electrolytes, nerve impulses and muscle activity would be impaired, leading to serious physiological disturbances.

- Therefore, while electrolytes do influence metabolic enzyme activity to some extent, their main physiological importance lies in fluid homeostasis and neuromuscular function, not in oxygen transport or carbohydrate metabolism.

Reference: Guyton and Hall Textbook of Medical Physiology, 14th Edition, Chapter 2 - Fluid and Electrolyte Balance