During renal embryogenesis, what is the primary contribution of the ureteric bud?
A Formation of the nephron's glomerulus and tubules
B Development of the collecting duct system
C Differentiation of the renal interstitium
D Formation of the renal capsule and surrounding fat
Solution
Correct Answer: Option B
- During renal embryogenesis, the ureteric bud plays a crucial role in the formation of the kidney's collecting system.
- The ureteric bud arises from the mesonephric duct and interacts with the metanephric mesenchyme to orchestrate kidney development.
Key points:
- The ureteric bud gives rise to the collecting ducts, calyces, renal pelvis, and ureter.
- It induces the metanephric mesenchyme to differentiate into nephrons, including the glomerulus and renal tubules.
- The nephron structures themselves (glomerulus and tubules) originate from the metanephric mesenchyme, not from the ureteric bud.
- The renal interstitium and capsule arise from surrounding mesenchymal tissue, distinct from the ureteric bud.
Therefore, the primary contribution of the ureteric bud is the development of the collecting duct system, which serves as the drainage pathway for urine from the nephrons to the ureter.