What is the primary function of the pyloric sphincter in gastrointestinal physiology?

A Control the passage of chyme from the stomach to the duodenum

B Prevent bile reflux into the stomach

C Regulate gastric acid secretion

D Delay gastric emptying by closing the lower esophageal sphincter

Solution

Correct Answer: Option A

- The primary function of the pyloric sphincter is to control the passage of chyme from the stomach to the duodenum.
- This muscular valve is located at the junction between the stomach and the duodenum, and it plays a crucial role in digestive system regulation.
- By opening and closing, the pyloric sphincter ensures that partially digested food, or chyme, is released in a controlled and gradual manner into the small intestine for further digestion and nutrient absorption.

- This controlled emptying is important because it allows the duodenum enough time to neutralize stomach acid and optimally process the chyme with digestive enzymes and bile.
- The pyloric sphincter also prevents the backflow of duodenal contents into the stomach, protecting the gastric mucosa from irritation.

Other options are incorrect because:
- It does not prevent bile reflux, which is primarily managed by other mechanisms such as the Oddi sphincter.
- It does not regulate gastric acid secretion, a process controlled by gastric glands and hormonal signals like gastrin.
- It does not affect the lower esophageal sphincter, which controls the passage between the esophagus and the stomach.

In summary, the pyloric sphincter's role is essential in modulating gastric emptying and ensuring efficient digestion.

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