What is the primary function of osteoclasts in bone physiology?
Solution
Correct Answer: Option B
- The primary function of osteoclasts in bone physiology is to resorb bone tissue.
- Osteoclasts are specialized, multinucleated cells responsible for breaking down the mineralized bone matrix.
- This process is essential for bone remodeling, which maintains bone strength and calcium homeostasis. Unlike osteoblasts, which form new bone matrix, osteoclasts degrade old or damaged bone, allowing for the continuous renewal and repair of the skeletal system.
- This balanced activity between osteoclasts (bone resorption) and osteoblasts (bone formation) ensures proper bone density and structural integrity throughout life.
- Osteoclast dysfunction can lead to bone disorders such as osteoporosis or osteopetrosis.
Important points:
- Osteoclasts resorb bone tissue to maintain healthy bone remodeling.
- Their activity balances osteoblast function, which forms new bone.
- This process is vital for calcium homeostasis and skeletal maintenance.
Reference: Robbins Basic Pathology, 10th Edition, Chapter 14 - Bone Physiology, Page 565-570
- Osteoclasts are specialized, multinucleated cells responsible for breaking down the mineralized bone matrix.
- This process is essential for bone remodeling, which maintains bone strength and calcium homeostasis. Unlike osteoblasts, which form new bone matrix, osteoclasts degrade old or damaged bone, allowing for the continuous renewal and repair of the skeletal system.
- This balanced activity between osteoclasts (bone resorption) and osteoblasts (bone formation) ensures proper bone density and structural integrity throughout life.
- Osteoclast dysfunction can lead to bone disorders such as osteoporosis or osteopetrosis.
Important points:
- Osteoclasts resorb bone tissue to maintain healthy bone remodeling.
- Their activity balances osteoblast function, which forms new bone.
- This process is vital for calcium homeostasis and skeletal maintenance.
Reference: Robbins Basic Pathology, 10th Edition, Chapter 14 - Bone Physiology, Page 565-570
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