What is the typical glomerular filtration rate (GFR) range in a healthy adult individual?

A 90-100 mL/min

B 120-130 mL/min

C 150-160 mL/min

D 60-70 mL/min

Solution

Correct Answer: Option B

- The glomerular filtration rate (GFR) is a crucial indicator of kidney function, representing the volume of fluid filtered from the renal glomerular capillaries into the Bowman's capsule per minute.
- In healthy adult individuals, the typical GFR range is approximately 120-130 mL/min.
- This value ensures that the kidneys efficiently filter blood to maintain fluid and electrolyte balance, remove waste products, and regulate blood pressure.

- GFR can vary slightly depending on factors such as age, sex, body size, and hydration status.
- However, values significantly below this range (e.g., less than 60 mL/min) may indicate renal impairment or chronic kidney disease.
- Conversely, values much higher than the normal range are uncommon in a healthy adult and may suggest hyperfiltration, which can be a response to various pathological states.

Therefore, the option "120-130 mL/min" accurately reflects the typical GFR range in a healthy adult.

Reference: Guyton and Hall Textbook of Medical Physiology, 14th Edition, Chapter 26 / Page 310

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