The recommended fluoride concentration in toothpaste for adult use is 1000–1500 ppm.

- Fluoride plays a crucial role in the prevention of dental caries by enhancing the remineralization of enamel and inhibiting the demineralization process.
- Toothpastes containing fluoride concentrations within the range of 1000 to 1500 parts per million (ppm) have been extensively studied and proven effective in reducing the incidence of dental decay in adults.
- Concentrations below this range may not provide sufficient protection, while significantly higher concentrations (e.g., 2000–2500 ppm) are typically reserved for specific therapeutic or high-risk cases and should be used under professional supervision to avoid potential adverse effects such as dental fluorosis.

For most adults, the 1000–1500 ppm fluoride toothpaste strikes an optimal balance between efficacy and safety, making it the standard recommendation by dental health authorities worldwide.

Key Points:

- Fluoride concentration of 1000–1500 ppm is effective for caries prevention in adults.
- Lower concentrations may not provide adequate protection.
- Higher concentrations (>2000 ppm) are for special cases and require professional advice.
- Regular use of fluoride toothpaste is essential for maintaining oral health.

Reference: Fejerskov O, Kidd E. Dental Caries: The Disease and Its Clinical Management, 3rd Edition, Volume 1, Chapter 4, Page 62