- The correct answer is Neutrophil infiltration because neutrophils are the first responders to injury or infection in acute inflammation.
- They quickly migrate to the site, where they perform phagocytosis and release enzymes to eliminate pathogens.
- In contrast, eosinophils, lymphocytes, and macrophages are more characteristic of chronic inflammation or specific immune responses.

Thus, neutrophil predominance is the hallmark of acute inflammation.

Reference: Robbins Basic Pathology, 10th Edition, Chapter 2/ Page 44