Coagulative necrosis is characteristically seen in which of the following conditions?
Solution
Correct Answer: Option A
- Coagulative necrosis is characterized by the preservation of tissue architecture for days after cell death, mainly due to protein denaturation.
- It is typically seen in ischemic infarcts of solid organs like the heart (myocardial infarction).
- In myocardial infarction, lack of blood supply causes cell death, but the tissue structure remains intact initially.
- This contrasts with brain infarction and abscesses, which exhibit liquefactive necrosis, and tuberculosis, which shows caseous necrosis.
Reference: Robbins Basic Pathology, 10th Edition, Chapter 2 – Cell Injury and Death, Page 45