Which clinical feature distinguishes shigellosis from cholera?
A Profuse watery diarrhea without blood
B Presence of bloody diarrhea
C Severe vomiting and dehydration
D Rice-water stools
Solution
Correct Answer: Option B
- The key clinical difference is that shigellosis causes invasive colitis, leading to inflammation and ulceration of the intestinal mucosa, which results in bloody diarrhea (dysentery).
- In contrast, cholera is a non-invasive infection caused by Vibrio cholerae, characterized by the secretion of a toxin that induces profuse watery diarrhea without blood.
Thus, presence of bloody diarrhea distinguishes shigellosis from cholera.
Reference: Robbins Basic Pathology, 10th Edition, Chapter 13 / Page 545