- Albendazole works by binding to parasite β-tubulin, which inhibits microtubule polymerization.
- This disruption impairs essential cellular processes like glucose uptake and intracellular transport, leading to energy depletion and parasite death.
- Unlike options involving neurotransmitter or DNA synthesis interference, albendazole specifically targets the cytoskeletal structure unique to parasites, making microtubule inhibition the primary antiparasitic mechanism.

Reference: Katzung BG, Basic and Clinical Pharmacology, 15th Edition, Chapter 48/ Page 670