Which of the following clinical manifestations is most characteristic of disseminated gonococcal infection (DGI)?
A Arthritis-dermatitis syndrome
B Meningitis with cranial nerve palsies
C Hemorrhagic cystitis
D Necrotizing fasciitis
Solution
Correct Answer: Option A
- The correct answer is Arthritis-dermatitis syndrome because it is the classic presentation of disseminated gonococcal infection (DGI).
- This syndrome typically includes polyarthralgia or migratory arthritis, along with characteristic pustular skin lesions.
- DGI results from hematogenous spread of Neisseria gonorrhoeae. Other options like meningitis, cystitis, or necrotizing fasciitis are not typical manifestations of DGI.
Reference: Harrison's Principles of Internal Medicine, 20th Edition, Infectious Diseases Chapter