In a peripheral blood film, Wright-Giemsa stain is primarily used to identify which of the following?
A Morphology of red blood cells
B Identification of serum proteins
C Detection of blood clotting factors
D Visualization of platelet aggregation
Solution
Correct Answer: Option A
- Wright-Giemsa stain is a polychromatic stain commonly used in hematology to differentiate cellular components in blood smears.
- It binds to acidic and basic cellular structures, allowing clear visualization of red blood cell morphology, white blood cell types, and platelets.
- This stain highlights features like cell size, shape, and hemoglobin content, crucial for diagnosing hematologic disorders.
- It is not used for detecting serum proteins, clotting factors, or platelet aggregation.
Reference: Robbins Basic Pathology, 10th Edition, Chapter 7, Blood Cells