The presence of leukocyte esterase and nitrites on a urine dipstick most strongly indicates:
Solution
Correct Answer: Option A
- The presence of leukocyte esterase indicates white blood cells (WBCs) in the urine, suggesting inflammation or infection.
- Nitrites are produced by many gram-negative bacteria that convert urinary nitrates to nitrites.
- Together, these findings strongly suggest a bacterial urinary tract infection (UTI).
Other options like interstitial nephritis, nephrolithiasis, and glomerulonephritis do not typically produce both leukocyte esterase and nitrites on dipstick.
Reference: Harrison's Principles of Internal Medicine, 20th Edition, Chapter 281/ Page 1989
- Nitrites are produced by many gram-negative bacteria that convert urinary nitrates to nitrites.
- Together, these findings strongly suggest a bacterial urinary tract infection (UTI).
Other options like interstitial nephritis, nephrolithiasis, and glomerulonephritis do not typically produce both leukocyte esterase and nitrites on dipstick.
Reference: Harrison's Principles of Internal Medicine, 20th Edition, Chapter 281/ Page 1989
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