Which of the following describes the primary role of telomerase in cellular biology?

A Repair damaged DNA strands following replication errors

B Extend telomeres to prevent progressive chromosomal shortening

C Initiate synthesis of RNA primers during DNA replication

D Facilitate DNA unwinding by breaking hydrogen bonds between bases

Solution

Correct Answer: Option B

- Telomerase is an enzyme that adds repetitive nucleotide sequences to the ends of chromosomes, known as telomeres.
- This process prevents the progressive shortening of chromosomes that occurs during DNA replication.
- Without telomerase, critical genetic information could be lost, leading to cellular aging and death.

Therefore, its primary role is to maintain chromosome integrity by extending telomeres.

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