- Regular use of insecticide spraying in mosquito breeding areas is most effective in controlling dengue fever because dengue is transmitted by Aedes mosquitoes, primarily Aedes aegypti.
- Interrupting the mosquito lifecycle by targeting breeding sites with insecticides reduces the vector population, thereby decreasing transmission rates.
- There are no specific antiviral drugs or universally recommended vaccines for dengue prevention applicable to all populations, and antibiotics have no role as dengue is a viral illness.
- Vector control remains the cornerstone of dengue prevention and outbreak control.

Reference: Davidson’s Principles and Practice of Medicine, 23rd Edition, Chapter: Tropical Medicine and Infectious Disease, Page 805.