Formaldehyde-containing root canal sealers release formaldehyde, which has potent antimicrobial and fixative properties. This makes them suitable primarily for temporary pulpotomy procedures where rapid tissue fixation and bacterial control are desired. However, due to their toxicity and potential tissue irritation, they are not recommended for permanent obturation or direct pulp capping. Their use in temporary pulpotomy helps in controlling hemorrhage and preventing bacterial infiltration effectively until further treatment. Thus, these sealers are best indicated in temporary treatments rather than long-term root canal therapy.

Reference: Grossman’s Endodontic Practice, 13th Edition.