Primary intention healing occurs when surgical wounds are closed immediately with suturing, staples, or adhesive strips, allowing the wound edges to be precisely approximated. This results in minimal tissue loss, reduced inflammation, and faster healing with minimal scarring. Primary closure promotes optimal conditions for regeneration of the epithelium and connective tissue without significant granulation tissue formation. It contrasts with secondary and tertiary intention, where wounds heal by granulation or delayed closure. Thus, primary intention is the hallmark of immediate wound closure and rapid restoration of tissue integrity after surgery.

Reference: Schwartz’s Principles of Surgery, 11th Edition.