The interocclusal distance at rest in the premolar region typically measures 2-4 mm, which represents the physiologic freeway space between the maxillary and mandibular teeth when the mandible is at rest. This space is crucial for normal muscle function and comfort, preventing constant tooth contact that could lead to muscle fatigue or temporomandibular joint issues. Accurate assessment ensures proper occlusal vertical dimension during prosthetic rehabilitation or orthodontic treatment. Maintaining this space avoids excessive strain on the masticatory system and helps achieve functional stability.

Reference: Oral Physiology, Wheeler’s Dental Anatomy, Physiology and Occlusion, Ash & Nelson, 10th Edition.