Medico-legal specimens must be transported in sealed, tamper-proof containers to maintain the chain of custody and ensure the integrity and authenticity of the evidence. This prevents contamination, loss, or alteration, which could compromise legal proceedings. Using sealed containers also provides clear evidence that the specimen has not been interfered with since collection. Proper labeling and secure packaging are essential to avoid mix-ups and preserve specimen quality for accurate analysis. This protocol upholds legal and ethical standards during specimen handling and transport.

Reference: Forensic Medicine, K.S. Narayan Reddy, 5th Edition.