Which oral manifestation is most commonly seen in iron deficiency anemia?

A Atrophic glossitis and angular cheilitis

B Leukoplakia

C Oral lichen planus

D Geographic tongue

Solution

Correct Answer: Option A

Atrophic glossitis presents as a smooth, shiny tongue due to papillary atrophy, and angular cheilitis involves inflammation and fissuring at the corners of the mouth. Both are classic oral manifestations of iron deficiency anemia caused by impaired epithelial cell renewal and iron’s role in maintaining mucosal integrity. These changes result from iron’s essential function in oxygen transport and epithelial metabolism, leading to mucosal atrophy and susceptibility to secondary infections. Leukoplakia, oral lichen planus, and geographic tongue are not specific to iron deficiency anemia.

Reference: Oral Pathology, Neville et al., 4th Edition.

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