The presentation of recurrent oral ulcers, genital ulcers, and uveitis is characteristic of Behçet’s disease, a chronic, multisystem vasculitis. This triad is highly suggestive and differentiates it from other causes of ulcers. Recurrent mucocutaneous ulcerations combined with ocular inflammation (specifically uveitis) are hallmark features and key to diagnosis. Unlike aphthous ulcers or herpetic stomatitis, Behçet’s involves genital ulcers and significant systemic involvement. Stevens-Johnson syndrome typically presents with acute mucocutaneous blistering, not recurrent ulcers or isolated uveitis.

Reference: Harrison’s Principles of Internal Medicine, Jameson et al., 20th Edition.