The markedly elevated serum amylase and lipase levels are classic biochemical markers for acute pancreatitis. Both enzymes, especially lipase, are highly sensitive and specific for pancreatic inflammation. The elevated WBC count indicates an inflammatory response. Unlike other acute abdominal conditions listed, acute pancreatitis presents with these significant enzyme elevations due to pancreatic cell injury and enzyme leakage into the bloodstream. Prompt recognition is crucial as early supportive care and monitoring for complications significantly affect outcomes.

Reference: Sabiston Textbook of Surgery, Townsend et al., 21st Edition.