What is a common cause of developmental genital anomalies?
Solution
Correct Answer: Option A
Müllerian duct maldevelopment is a common cause of developmental genital anomalies because these ducts are precursors to the female internal reproductive organs, including the fallopian tubes, uterus, cervix, and upper vagina. Failure in the proper formation, fusion, or resorption of the Müllerian ducts leads to structural abnormalities such as uterine agenesis, bicornuate uterus, or septate uterus. These anomalies can impact fertility, pregnancy outcomes, and may require surgical correction like metroplasty. Recognizing Müllerian duct anomalies is crucial for appropriate diagnosis and management of congenital genital tract malformations.
Reference: Williams Gynecology, Hoffman et al., 3rd Edition.