What is a key risk factor for hepatitis E in pregnancy?
Solution
Correct Answer: Option A
Hepatitis E virus (HEV) is primarily transmitted via the fecal-oral route, most commonly through ingestion of contaminated water. In pregnant women, especially in the third trimester, HEV infection can cause severe disease with a high risk of fulminant hepatitis and maternal mortality. This heightened severity is linked to immune and hormonal changes during pregnancy. Therefore, contaminated water remains the key risk factor for hepatitis E in pregnancy, emphasizing the importance of safe water sources to prevent infection.
Reference: Harrison's Principles of Internal Medicine, Kasper et al., 20th Edition.
Reference: Harrison's Principles of Internal Medicine, Kasper et al., 20th Edition.
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