What is the typical resting membrane potential of a neuron?
Solution
Correct Answer: Option A
The typical resting membrane potential of a neuron is -70 millivolts because this value reflects the balance of ion distribution across the neuronal membrane, primarily due to the high permeability of potassium ions (K⁺) and the action of the sodium-potassium pump. This negative potential is essential for maintaining neuronal excitability and enabling the generation of action potentials. Deviations from this resting potential can lead to altered nerve function and are critical in various neurological conditions. The other options represent depolarized states or are not physiologically relevant resting potentials.
Reference: Guyton and Hall Textbook of Medical Physiology, Arthur C. Guyton, 13th Edition.