Gonadotropin-releasing hormone (GnRH) is secreted by the hypothalamus and acts on the anterior pituitary gland to directly stimulate the release of the gonadotropins: luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones regulate the function of the ovaries and testes, controlling processes such as ovulation and spermatogenesis. GnRH does not stimulate the release of other pituitary hormones like TSH, ACTH, prolactin, GH, insulin, or glucagon. Understanding this axis is crucial in managing reproductive endocrinology disorders and infertility.

Reference: Ganong's Review of Medical Physiology, Barrett KE, 26th Edition.