The correct answer is Calcifying epithelial odontogenic cyst because it is a rare and distinct lesion that typically presents as a mixed radiolucent-radiopaque lesion rather than a purely pericoronal radiolucency. In contrast, Dentigerous cyst, Unicystic ameloblastoma, and Odontogenic keratocyst commonly present as well-defined pericoronal radiolucencies associated with the crown of an unerupted tooth. Recognizing this is critical for surgical planning, as misdiagnosis may lead to inappropriate management. Accurate identification guides surgical enucleation or resection and follow-up, ensuring optimal outcomes.

Reference: Oral Pathology, Neville et al., 4th Edition.