Dentinogenesis imperfecta is a hereditary condition characterized by defective formation and mineralization of dentine, leading to discolored, weak, and translucent teeth. The dentine in these teeth is structurally abnormal, causing enamel to fracture easily due to lack of proper support. Unlike enamel defects, dentinogenesis imperfecta affects the primary and permanent dentition and also impacts the pulp chamber and root dentine. This disorder results in tooth sensitivity, rapid wear, and increased risk of fracture. The primary pathological change is in the dentine matrix formation and mineralization, directly causing the clinical manifestations observed.

Reference: Shafer's Textbook of Oral Pathology, Rajendran R., 7th Edition.